Hepatic Crown-Like Structure: A Unique Histological Feature in Non-Alcoholic Steatohepatitis in Mice and Humans

• Michiko Itoh ,

  Contributed equally to this work with: Michiko Itoh, Hideaki Kato

  Affiliation Department of Organ Network and Metabolism, Tokyo Medical and Dental University, Tokyo, Japan

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• Hideaki Kato ,

  Contributed equally to this work with: Michiko Itoh, Hideaki Kato

  Affiliations Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan, Medical Research Laboratories, Shionogi & Co. Ltd., Osaka, Japan

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• Takayoshi Suganami ,

  * E-mail: ogawa.mem@tmd.ac.jp (YO); suganami.mem@tmd.ac.jp (TS)

  Affiliations Department of Organ Network and Metabolism, Tokyo Medical and Dental University, Tokyo, Japan, Japan Science and Technology Agency, PRESTO, Tokyo, Japan

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• Kuniha Konuma,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Yoshio Marumoto,

  Affiliation Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

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• Shuji Terai,

  Affiliation Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

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• Hiroshi Sakugawa,

  Affiliation Heart Life Hospital, Okinawa, Japan

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• Sayaka Kanai,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Miho Hamaguchi,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Takahiro Fukaishi,

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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• Seiichiro Aoe,

  Affiliation Department of Home Economics, Otsuma Women's University, Tokyo, Japan

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• Kazunari Akiyoshi,

  Affiliation Department of Polymer Chemistry, Kyoto University Graduate School of Engineering, Kyoto, Japan

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• Yoshihiro Komohara,

  Affiliation Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan

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• Motohiro Takeya,

  Affiliation Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan

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• Isao Sakaida,

  Affiliation Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan

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•  [ ... ],
• Yoshihiro Ogawa

  * E-mail: ogawa.mem@tmd.ac.jp (YO); suganami.mem@tmd.ac.jp (TS)

  Affiliation Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

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