Both Positive and Negative Selection Pressures Contribute to the Polymorphism Pattern of the Duplicated Human CYP21A2 Gene

• Julianna Anna Szabó,

  Affiliation 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• Ágnes Szilágyi,

  Affiliation 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• Zoltán Doleschall,

  Affiliation Department of Pathogenetics, National Institute of Oncology, Budapest, Hungary

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• Attila Patócs,

  Affiliations Molecular Medicine Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary, “Lendület” Hereditary Endocrine Tumours Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary

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• Henriette Farkas,

  Affiliation 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• Zoltán Prohászka,

  Affiliation 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• Kárioly Rácz,

  Affiliations Molecular Medicine Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary, 2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• George Füst †,

  † Deceased.

  Affiliation 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary

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• Márton Doleschall

  * E-mail: doleschall@med.semmelweis-univ.hu

  Affiliations 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary, Molecular Medicine Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary

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