New Therapeutic Approach: Diphenyl Diselenide Reduces Mitochondrial Dysfunction in Acetaminophen-Induced Acute Liver Failure

Nélson R. Carvalho; Edovando F. da Rosa; Michele H. da Silva; Cintia C. Tassi; Cristiane L. Dalla Corte; Sara Carbajo-Pescador; Jose L. Mauriz; Javier González-Gallego; Félix A. Soares

doi:10.1371/journal.pone.0081961

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Open Access

Peer-reviewed

Research Article

New Therapeutic Approach: Diphenyl Diselenide Reduces Mitochondrial Dysfunction in Acetaminophen-Induced Acute Liver Failure

Nélson R. Carvalho,

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯
Edovando F. da Rosa,

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯
Michele H. da Silva,

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯
Cintia C. Tassi,

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯
Cristiane L. Dalla Corte,

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯
Sara Carbajo-Pescador,

Affiliation Institute of Biomedicine (IBIOMED) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of León, León, Spain
⨯
Jose L. Mauriz,

Affiliation Institute of Biomedicine (IBIOMED) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of León, León, Spain
⨯
Javier González-Gallego,

Affiliation Institute of Biomedicine (IBIOMED) and Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), University of León, León, Spain
⨯
Félix A. Soares

* E-mail: felix@ufsm.br

Affiliation Departamento de Química, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Campus UFSM, Santa Maria, Rio Grande do Sul, Brasil
⨯

New Therapeutic Approach: Diphenyl Diselenide Reduces Mitochondrial Dysfunction in Acetaminophen-Induced Acute Liver Failure

Nélson R. Carvalho,
Edovando F. da Rosa,
Michele H. da Silva,
Cintia C. Tassi,
Cristiane L. Dalla Corte,
Sara Carbajo-Pescador,
Jose L. Mauriz,
Javier González-Gallego,
Félix A. Soares

Published: December 11, 2013
https://doi.org/10.1371/journal.pone.0081961

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