Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury

Daniel Kim; Laila Zai; Peng Liang; Colleen Schaffling; David Ahlborn; Larry I. Benowitz

doi:10.1371/journal.pone.0081948

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Peer-reviewed

Research Article

Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury

Daniel Kim,

Affiliations Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America, F.M. Kirby Neurobiology Center, Children’s Hospital, Boston, Massachusetts, United States of America
⨯
Laila Zai,

Affiliations Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America, F.M. Kirby Neurobiology Center, Children’s Hospital, Boston, Massachusetts, United States of America, Surgery Department, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Peng Liang,

Current address: Neurosurgery Department, Harbin Medical University, Harbin, China

Affiliations Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America, F.M. Kirby Neurobiology Center, Children’s Hospital, Boston, Massachusetts, United States of America, Surgery Department, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Colleen Schaffling,

Affiliation Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America
⨯
David Ahlborn,

Affiliation Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America
⨯
Larry I. Benowitz

* Email: larry.benowitz@childrens.harvard.edu

Affiliations Laboratories for Neuroscience Research in Neurosurgery, Children’s Hospital, Boston, Massachusetts, United States of America, F.M. Kirby Neurobiology Center, Children’s Hospital, Boston, Massachusetts, United States of America, Surgery Department, Harvard Medical School, Boston, Massachusetts, United States of America, Ophthalmology Department, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Inosine Enhances Axon Sprouting and Motor Recovery after Spinal Cord Injury

Daniel Kim,
Laila Zai,
Peng Liang,
Colleen Schaffling,
David Ahlborn,
Larry I. Benowitz

Published: December 2, 2013
https://doi.org/10.1371/journal.pone.0081948

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Inosine
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Axons
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Rats
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Spinal cord
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Spinal cord injury
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Biological locomotion
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Synapses
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Neural circuit formation
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