Systems Biology Analysis of Brucella Infected Peyer's Patch Reveals Rapid Invasion with Modest Transient Perturbations of the Host Transcriptome

Carlos A. Rossetti; Kenneth L. Drake; Prasad Siddavatam; Sara D. Lawhon; Jairo E. S. Nunes; Tamara Gull; Sangeeta Khare; Robin E. Everts; Harris A. Lewin; Leslie Garry Adams

doi:10.1371/journal.pone.0081719

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Peer-reviewed

Research Article

Systems Biology Analysis of Brucella Infected Peyer's Patch Reveals Rapid Invasion with Modest Transient Perturbations of the Host Transcriptome

Carlos A. Rossetti,

Current address: Instituto de Patobiología, Centro Nacional de Investigaciones Agropecuarias, Buenos Aires, Argentina

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
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Kenneth L. Drake,

Affiliation Seralogix, Limited Liability Corporation, Austin, Texas, United States of America
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Prasad Siddavatam,

Affiliation Seralogix, Limited Liability Corporation, Austin, Texas, United States of America
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Sara D. Lawhon,

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
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Jairo E. S. Nunes,

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
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Tamara Gull,

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯
Sangeeta Khare,

Current address: National Center for Toxicological Research, US-Food and Drug Administration, Jefferson, Arkansas, United States of America

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯
Robin E. Everts,

Current address: Sequenom Incorporated, San Diego, California, United States of America

Affiliation Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
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Harris A. Lewin,

Affiliation Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
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Leslie Garry Adams

* E-mail: gadams@cvm.tamu.edu

Affiliation Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, United States of America
⨯

Systems Biology Analysis of Brucella Infected Peyer's Patch Reveals Rapid Invasion with Modest Transient Perturbations of the Host Transcriptome

Carlos A. Rossetti,
Kenneth L. Drake,
Prasad Siddavatam,
Sara D. Lawhon,
Jairo E. S. Nunes,
Tamara Gull,
Sangeeta Khare,
Robin E. Everts,
Harris A. Lewin,
Leslie Garry Adams

Published: December 9, 2013
https://doi.org/10.1371/journal.pone.0081719

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Brucella
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Gene expression
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Gene ontologies
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Peyer's patches
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Toll-like receptors
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Integrins
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Gene mapping
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Immune response
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