Increased B Cell and Cytotoxic NK Cell Proportions and Increased T Cell Responsiveness in Blood of Natalizumab-Treated Multiple Sclerosis Patients

Johan Mellergård; Måns Edström; Maria C. Jenmalm; Charlotte Dahle; Magnus Vrethem; Jan Ernerudh

doi:10.1371/journal.pone.0081685

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Peer-reviewed

Research Article

Increased B Cell and Cytotoxic NK Cell Proportions and Increased T Cell Responsiveness in Blood of Natalizumab-Treated Multiple Sclerosis Patients

Johan Mellergård ,

Contributed equally to this work with: Johan Mellergård, Måns Edström

* E-mail: johan.mellergard@lio.se

Affiliation Neurology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, and Department of Neurology, County Council of Östergötland, Linköping, Sweden
⨯
Måns Edström ,

Contributed equally to this work with: Johan Mellergård, Måns Edström

Affiliation Clinical Immunology, Unit of Autoimmunity and Immune Regulation, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden
⨯
Maria C. Jenmalm,

Affiliation Clinical Immunology, Unit of Autoimmunity and Immune Regulation, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden
⨯
Charlotte Dahle,

Affiliation Department of Clinical Immunology and Transfusion Medicine, County Council of Östergötland, Linköping, Sweden
⨯
Magnus Vrethem,

Affiliation Neurology and Clinical Neurophysiology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, and Department of Neurology and Neurophysiology, County Council of Östergötland, Linköping, Sweden
⨯
Jan Ernerudh

Affiliations Clinical Immunology, Unit of Autoimmunity and Immune Regulation, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden, Department of Clinical Immunology and Transfusion Medicine, County Council of Östergötland, Linköping, Sweden
⨯

Increased B Cell and Cytotoxic NK Cell Proportions and Increased T Cell Responsiveness in Blood of Natalizumab-Treated Multiple Sclerosis Patients

Johan Mellergård,
Måns Edström,
Maria C. Jenmalm,
Charlotte Dahle,
Magnus Vrethem,
Jan Ernerudh

Published: December 2, 2013
https://doi.org/10.1371/journal.pone.0081685

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Multiple sclerosis
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