Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs; Marcus J. Calkins; Ajit Jadhav; Dorjbal Dorjsuren; David Maloney; Anton Simeonov; Pawel Jaruga; Miral Dizdaroglu; Amanda K. McCullough; R. Stephen Lloyd

doi:10.1371/journal.pone.0081667

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Peer-reviewed

Research Article

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs,

Affiliation Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, United States of America
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Marcus J. Calkins,

Affiliation Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, United States of America
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Ajit Jadhav,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America
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Dorjbal Dorjsuren,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America
⨯
David Maloney,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Anton Simeonov,

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America
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Pawel Jaruga,

Affiliation Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America
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Miral Dizdaroglu,

Affiliation Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland, United States of America
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Amanda K. McCullough,

Affiliations Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, United States of America, Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America
⨯
R. Stephen Lloyd

* E-mail: lloydst@ohsu.edu

Affiliations Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, Oregon, United States of America, Department of Molecular and Medical Genetics, Oregon Health and Science University, Portland, Oregon, United States of America
⨯

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

Aaron C. Jacobs,
Marcus J. Calkins,
Ajit Jadhav,
Dorjbal Dorjsuren,
David Maloney,
Anton Simeonov,
Pawel Jaruga,
Miral Dizdaroglu,
Amanda K. McCullough,
R. Stephen Lloyd

Published: December 9, 2013
https://doi.org/10.1371/journal.pone.0081667

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Library screening
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