A Truncated Receptor-Binding Domain of MERS-CoV Spike Protein Potently Inhibits MERS-CoV Infection and Induces Strong Neutralizing Antibody Responses: Implication for Developing Therapeutics and Vaccines

• Lanying Du ,

  Contributed equally to this work with: Lanying Du, Zhihua Kou

  Affiliation Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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• Zhihua Kou ,

  Contributed equally to this work with: Lanying Du, Zhihua Kou

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Cuiqing Ma,

  Affiliation Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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• Xinrong Tao,

  Affiliation Departments of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Lili Wang,

  Affiliation Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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• Guangyu Zhao,

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Yaoqing Chen,

  Affiliation Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America

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• Fei Yu,

  Affiliation Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America

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• Chien-Te K. Tseng,

  Affiliation Departments of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, United States of America

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• Yusen Zhou ,

  * E-mail: sjiang@nybloodcenter.org (SJ); yszhou@bmi.ac.cn (YZ)

  Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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• Shibo Jiang

  * E-mail: sjiang@nybloodcenter.org (SJ); yszhou@bmi.ac.cn (YZ)

  Affiliations Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, United States of America, Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College and Institute of Medical Microbi, Fudan University, Shanghai, China

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