Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation

Huiting Ho; Harmeet Singh; Sophea Heng; Tracy L. Nero; Sarah Paule; Michael W. Parker; Alan T. Johnson; Guan-Sheng Jiao; Guiying Nie

doi:10.1371/journal.pone.0081380

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Peer-reviewed

Research Article

Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation

Huiting Ho,

Affiliations Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
⨯
Harmeet Singh,

Affiliation Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia
⨯
Sophea Heng,

Affiliations Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
⨯
Tracy L. Nero,

Affiliation Biota Structural Biology Laboratory and ACRF Rational Drug Discovery Centre, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia
⨯
Sarah Paule,

Affiliation Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia
⨯
Michael W. Parker,

Affiliations Biota Structural Biology Laboratory and ACRF Rational Drug Discovery Centre, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia, Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia
⨯
Alan T. Johnson,

Affiliation Department of Chemistry, PanThera Biopharma LLC, Aiea, Hawaii, United States of America
⨯
Guan-Sheng Jiao ,

* E-mail: guiying.nie@princehenrys.org (GN); gjiao@pantherabio.com (GSJ)

Affiliation Department of Chemistry, PanThera Biopharma LLC, Aiea, Hawaii, United States of America
⨯
Guiying Nie

* E-mail: guiying.nie@princehenrys.org (GN); gjiao@pantherabio.com (GSJ)

Affiliations Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia, Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia
⨯

Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation

Huiting Ho,
Harmeet Singh,
Sophea Heng,
Tracy L. Nero,
Sarah Paule,
Michael W. Parker,
Alan T. Johnson,
Guan-Sheng Jiao,
Guiying Nie

Published: December 4, 2013
https://doi.org/10.1371/journal.pone.0081380

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