Identification of a Novel Zinc Metalloprotease through a Global Analysis of Clostridium difficile Extracellular Proteins

Open Access

Peer-reviewed

Research Article

Valeria Cafardi,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
⨯
Massimiliano Biagini,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
⨯
Manuele Martinelli,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
⨯
Rosanna Leuzzi,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
⨯
Jeffrey T. Rubino,

Affiliation Magnetic Resonance Center, University of Florence, Sesto Fiorentino, Italy
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Francesca Cantini,

Affiliations Magnetic Resonance Center, University of Florence, Sesto Fiorentino, Italy, Department of Chemistry, University of Florence, Sesto Fiorentino, Italy
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Nathalie Norais,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
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Maria Scarselli,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
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Davide Serruto,

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
⨯
Meera Unnikrishnan

* E-mail: m.unnikrishnan@warwick.ac.uk

Affiliation Novartis Vaccines and Diagnostics, Siena, Italy
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Clostridium difficile
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Zinc
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Fibrinogen
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Recombinant proteins
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Metalloproteases
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Toxins
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Cell walls
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Pathogenesis
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