Norisoboldine Suppresses VEGF-Induced Endothelial Cell Migration via the cAMP-PKA-NF-κB/Notch1 Pathway

Qian Lu; Bei Tong; Yubin Luo; Li Sha; Guixin Chou; Zhengtao Wang; Yufeng Xia; Yue Dai

doi:10.1371/journal.pone.0081220

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Peer-reviewed

Research Article

Norisoboldine Suppresses VEGF-Induced Endothelial Cell Migration via the cAMP-PKA-NF-κB/Notch1 Pathway

Qian Lu ,

Contributed equally to this work with: Qian Lu, Bei Tong

Affiliation State Key Laboratory of Natural Medicines, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China
⨯
Bei Tong ,

Contributed equally to this work with: Qian Lu, Bei Tong

Affiliation State Key Laboratory of Natural Medicines, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China
⨯
Yubin Luo,

Affiliation State Key Laboratory of Natural Medicines, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China
⨯
Li Sha,

Affiliation Department of Pediatrics, Nanjing Maternal and Child Health Hospital of Nanjing Medical University, Nanjing, China
⨯
Guixin Chou,

Affiliation Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Zhengtao Wang,

Affiliation Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China
⨯
Yufeng Xia ,

* E-mail: yfxiacpu@126.com (YX); yuedaicpu@hotmail.com (YD)

Affiliation State Key Laboratory of Natural Medicines, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China
⨯
Yue Dai

* E-mail: yfxiacpu@126.com (YX); yuedaicpu@hotmail.com (YD)

Affiliation State Key Laboratory of Natural Medicines, Department of Pharmacology of Chinese Materia Medica, China Pharmaceutical University, Nanjing, China
⨯

Norisoboldine Suppresses VEGF-Induced Endothelial Cell Migration via the cAMP-PKA-NF-κB/Notch1 Pathway

Qian Lu,
Bei Tong,
Yubin Luo,
Li Sha,
Guixin Chou,
Zhengtao Wang,
Yufeng Xia,
Yue Dai

Published: December 9, 2013
https://doi.org/10.1371/journal.pone.0081220

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