Torsadogenic Risk of Antipsychotics: Combining Adverse Event Reports with Drug Utilization Data across Europe

Emanuel Raschi; Elisabetta Poluzzi; Brian Godman; Ariola Koci; Ugo Moretti; Marija Kalaba; Marion Bennie; Corrado Barbui; Bjorn Wettermark; Miriam Sturkenboom; Fabrizio De Ponti

doi:10.1371/journal.pone.0081208

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Open Access

Peer-reviewed

Research Article

Torsadogenic Risk of Antipsychotics: Combining Adverse Event Reports with Drug Utilization Data across Europe

Emanuel Raschi,

Affiliation Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy
⨯
Elisabetta Poluzzi,

Affiliation Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy
⨯
Brian Godman,

Affiliations Division of Clinical Pharmacology, Karolinska Institute, Stockholm, Sweden, Strathclyde Institute of Pharmacy and Biomedical Sciences, Strathclyde University, Glasgow, United Kingdom
⨯
Ariola Koci,

Affiliation Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy
⨯
Ugo Moretti,

Affiliation Clinical Pharmacology Unit, University of Verona, Verona, Italy
⨯
Marija Kalaba,

Affiliation Republic Institute for Health Insurance, Belgrade, Serbia
⨯
Marion Bennie,

Affiliations Strathclyde Institute of Pharmacy and Biomedical Sciences, Strathclyde University, Glasgow, United Kingdom, Information Services Division, NHS National Services Scotland, Edinburgh, United Kingdom
⨯
Corrado Barbui,

Affiliation WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Public Health and Community Medicine, Section of Psychiatry, University of Verona, Verona, Italy
⨯
Bjorn Wettermark,

Affiliations Division of Clinical Pharmacology, Karolinska Institute, Stockholm, Sweden, Centre for Pharmacoepidemiology, Karolinska University Hospital, Solna, Stockholm, Sweden
⨯
Miriam Sturkenboom,

Affiliation Erasmus University Medical Centre, Rotterdam, The Netherlands
⨯
Fabrizio De Ponti

* E-mail: fabrizio.deponti@unibo.it

Affiliation Department of Medical and Surgical Sciences, Alma Mater Studiorum - University of Bologna, Bologna, Italy
⨯

Torsadogenic Risk of Antipsychotics: Combining Adverse Event Reports with Drug Utilization Data across Europe

Emanuel Raschi,
Elisabetta Poluzzi,
Brian Godman,
Ariola Koci,
Ugo Moretti,
Marija Kalaba,
Marion Bennie,
Corrado Barbui,
Bjorn Wettermark,
Miriam Sturkenboom

Published: November 20, 2013
https://doi.org/10.1371/journal.pone.0081208

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