A Broad Phenotypic Screen Identifies Novel Phenotypes Driven by a Single Mutant Allele in Huntington’s Disease CAG Knock-In Mice

• Sabine M. Hölter ,

  Contributed equally to this work with: Sabine M. Hölter, Mary Stromberg

  Affiliation German Mouse Clinic, Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Mary Stromberg ,

  Contributed equally to this work with: Sabine M. Hölter, Mary Stromberg

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Marina Kovalenko,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Lillian Garrett,

  Affiliation German Mouse Clinic, Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Lisa Glasl,

  Affiliation German Mouse Clinic, Institute of Developmental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Edith Lopez,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Jolene Guide,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Alexander Götz,

  Affiliation Comprehensive Pneumology Center, Institute of Lung Biology and Disease, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Wolfgang Hans,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Lore Becker,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Birgit Rathkolb,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Jan Rozman,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Anja Schrewed,

  Affiliation Department of Medicine III, Division of Cardiology, University of Heidelberg, Heidelberg, Germany

  ⨯
• Martin Klingenspor,

  Affiliation Molecular Nutritional Medicine, Else Kröner-Fresenius Center and ZIEL Research Center for Nutrition and Food Sciences, Technische Universität München, Munich, Germany

  ⨯
• Thomas Klopstock,

  Affiliation Department of Neurology, Friedrich-Baur-Institute and German Center for Vertigo and Balance Disorders, Ludwig-Maximilians-Universität München, Munich, Germany

  ⨯
• Holger Schulz,

  Affiliation Institute of Epidemiology I, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Eckhard Wolf,

  Affiliation Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Munich, Germany

  ⨯
• Wolfgang Wursta,

  Affiliations Max Planck Institute of Psychiatry, Munich, Germany, Deutsches Zentrum für Neurodegenerative Erkrankungen, Standort München, Munich, Germany

  ⨯
• Tammy Gillis,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Hiroko Wakimoto,

  Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America;

  ⨯
• Jonathan Seidman,

  Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America;

  ⨯
• Marcy E. MacDonald,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Susan Cotman,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• Valérie Gailus-Durner,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Helmut Fuchs,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Martin Hrabě de Angelis,

  Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany

  ⨯
• Jong-Min Lee,

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
•  [ ... ],
• Vanessa C. Wheeler

  * E-mail: Wheeler@chgr.mgh.harvard.edu

  Affiliation Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  ⨯
• [ view all ]
• [ view less ]