Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord

Dong Liu; Chaoxu Liu; Junqiang Li; Kazem Azadzoi; Yun Yang; Zhou Fei; Kefeng Dou; Neil W. Kowall; Han-Pil Choi; Fernando Vieira; Jing-Hua Yang

doi:10.1371/journal.pone.0080779

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Open Access

Peer-reviewed

Research Article

Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord

Dong Liu ,

Contributed equally to this work with: Dong Liu, Chaoxu Liu, Junqiang Li

Affiliations Visiting scholars from Departments of Hepatobiliary Surgery, Gastroenterology and Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi, China, Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Chaoxu Liu ,

Contributed equally to this work with: Dong Liu, Chaoxu Liu, Junqiang Li

Affiliations Visiting scholars from Departments of Hepatobiliary Surgery, Gastroenterology and Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi, China, Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯
Junqiang Li ,

Contributed equally to this work with: Dong Liu, Chaoxu Liu, Junqiang Li

Affiliation Cancer Research Center, Shandong University School of Medicine, Jinan, Shandong, China
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Kazem Azadzoi,

Affiliation Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
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Yun Yang,

Affiliation Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
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Zhou Fei,

Affiliation Visiting scholars from Departments of Hepatobiliary Surgery, Gastroenterology and Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi, China
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Kefeng Dou,

Affiliation Visiting scholars from Departments of Hepatobiliary Surgery, Gastroenterology and Neurosurgery, Xijing Hospital, Fourth Military Medical University, Xian, Shaanxi, China
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Neil W. Kowall,

Affiliation Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
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Han-Pil Choi,

Affiliation Proteomics Facilities, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
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Fernando Vieira,

Affiliation ALS Therapy Development Institute, Cambridge, Massachusetts, United States of America
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Jing-Hua Yang

* E-mail: jyang@bu.edu

Affiliations Departments of Surgery, Neurology and Urology, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America, Cancer Research Center, Shandong University School of Medicine, Jinan, Shandong, China, Proteomics Facilities, VA Boston Healthcare System and Boston University School of Medicine, Boston, Massachusetts, United States of America
⨯

Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord

Dong Liu,
Chaoxu Liu,
Junqiang Li,
Kazem Azadzoi,
Yun Yang,
Zhou Fei,
Kefeng Dou,
Neil W. Kowall,
Han-Pil Choi,
Fernando Vieira

Published: December 2, 2013
https://doi.org/10.1371/journal.pone.0080779

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Spinal cord
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Immunoprecipitation
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Acetylation
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Lysine
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