MuSK Myasthenia Gravis IgG4 Disrupts the Interaction of LRP4 with MuSK but Both IgG4 and IgG1-3 Can Disperse Preformed Agrin-Independent AChR Clusters

Open Access

Peer-reviewed

Research Article

Inga Koneczny,

Affiliation Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Judith Cossins,

Affiliation Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Patrick Waters,

Affiliation Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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David Beeson,

Affiliation Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Angela Vincent

* E-mail: angela.vincent@ndcn.ox.ac.uk

Affiliation Neurosciences Group, Nuffield Department of Clinical Neurosciences, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
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Immunoprecipitation
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Antibodies
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Co-immunoprecipitation
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Endocytosis
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Flow cytometry
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Transfection
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Cell binding
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Myasthenia gravis
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