Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

Dingqing Feng; Jiao Wu; Yuan Tian; Hu Zhou; Ying Zhou; Weiping Hu; Weidong Zhao; Haiming Wei; Bin Ling; Chunhong Ma

doi:10.1371/journal.pone.0080657

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Open Access

Peer-reviewed

Research Article

Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

Dingqing Feng,

Affiliations Key Laboratory for Experimental Teratology of the Ministry of Education, Shandong University School of Medicine, Shandong, China, Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Jiao Wu,

Affiliation Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Yuan Tian,

Affiliation Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Hu Zhou,

Affiliation Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Ying Zhou,

Affiliations Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China, Department of Obstetric and Gynecology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Weiping Hu,

Affiliation Department of Obstetric and Gynecology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Weidong Zhao,

Affiliation Department of Obstetric and Gynecology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China
⨯
Haiming Wei,

Affiliation Institute of Immunology, Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Anhui, China
⨯
Bin Ling,

Affiliations Anhui Province Key Laboratory of Molecular Medicine, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China, Department of Obstetric and Gynecology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui, China, Department of Obstetric and Gynecology, China-Japan Friendship Hospital, Beijing, China
⨯
Chunhong Ma

* E-mail: machunhong@sdu.edu.cn

Affiliation Key Laboratory for Experimental Teratology of the Ministry of Education, Shandong University School of Medicine, Shandong, China
⨯

Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

Dingqing Feng,
Jiao Wu,
Yuan Tian,
Hu Zhou,
Ying Zhou,
Weiping Hu,
Weidong Zhao,
Haiming Wei,
Bin Ling,
Chunhong Ma

Published: November 19, 2013
https://doi.org/10.1371/journal.pone.0080657

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