A Novel Pulse-Chase SILAC Strategy Measures Changes in Protein Decay and Synthesis Rates Induced by Perturbation of Proteostasis with an Hsp90 Inhibitor

• Ivo Fierro-Monti,

  Affiliation Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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• Julien Racle,

  Affiliations Laboratory of Computational Systems Biotechnology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland

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• Celine Hernandez,

  Affiliations Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland, SIB Swiss Institute of Bioinformatics, Vital-IT group, Lausanne, Switzerland

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• Patrice Waridel,

  Affiliation Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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• Vassily Hatzimanikatis,

  Affiliations Laboratory of Computational Systems Biotechnology, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, SIB Swiss Institute of Bioinformatics, Lausanne, Switzerland

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• Manfredo Quadroni

  * E-mail: manfredo.quadroni@unil.ch

  Affiliation Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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