Branched-Chain Amino Acids Enhance Premature Senescence through Mammalian Target of Rapamycin Complex I-Mediated Upregulation of p21 Protein

• Masayuki Nakano,

  Affiliations Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan

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• Akio Nakashima,

  Affiliation Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, Kobe, Japan

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• Taiki Nagano,

  Affiliations Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan

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• Shintaro Ishikawa,

  Affiliation Otsuka Pharmaceutical Co., Ltd., Minato-ku, Tokyo, Japan

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• Ushio Kikkawa,

  Affiliations Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan

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• Shinji Kamada

  * E-mail: skamada@kobe-u.ac.jp

  Affiliations Biosignal Research Center, Organization of Advanced Science and Technology, Kobe University, Kobe, Japan, Department of Biology, Graduate School of Science, Kobe University, Kobe, Japan

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