Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain

• Hideaki Yamamoto,

  Affiliations Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan

  ⨯
• Tomohiko Maruo,

  Affiliations Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan

  ⨯
• Takashi Majima,

  Affiliations CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan, Department of Molecular Biology and Biochemistry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan, Department of Molecular Biology, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan

  ⨯
• Hiroyoshi Ishizaki,

  Affiliations CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan, Department of Molecular Biology, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan

  ⨯
• Miki Tanaka-Okamoto,

  Affiliations CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan, Department of Molecular Biology, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan

  ⨯
• Jun Miyoshi,

  Affiliations CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan, Department of Molecular Biology, Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan

  ⨯
• Kenji Mandai ,

  * E-mail: ytakai@med.kobe-u.ac.jp (KT); mandai@med.kobe-u.ac.jp (KM)

  Affiliations Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan

  ⨯
• Yoshimi Takai

  * E-mail: ytakai@med.kobe-u.ac.jp (KT); mandai@med.kobe-u.ac.jp (KM)

  Affiliations Division of Pathogenetic Signaling, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan, CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan, Department of Molecular Biology and Biochemistry, Osaka University Graduate School of Medicine, Suita, Osaka, Japan

  ⨯