EBV Infection Is Common in Gingival Epithelial Cells of the Periodontium and Worsens during Chronic Periodontitis

Séverine Vincent-Bugnas; Sébastien Vitale; Caroline C. Mouline; Wafa Khaali; Yves Charbit; Patrick Mahler; Isabelle Prêcheur; Paul Hofman; Janet L. Maryanski; Alain Doglio

doi:10.1371/journal.pone.0080336

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Peer-reviewed

Research Article

EBV Infection Is Common in Gingival Epithelial Cells of the Periodontium and Worsens during Chronic Periodontitis

Séverine Vincent-Bugnas,

Affiliations Université Nice-Sophia Antipolis, UFR Médecine, ImCelVir URE004, Nice, France, Université Nice-Sophia Antipolis, UFR Odontologie, LSBV URE001, Nice, France, Centre Hospitalier Universitaire de Nice, Pôle Odontologie, Hôpital Saint Roch, Nice, France, Centre Hospitalier Universitaire de Nice, Unité de Thérapie Cellulaire et Génique, Nice, France
⨯
Sébastien Vitale,

Current address: Laboratoire de Virologie, Hôpital de l'Archet II, Nice, France

Affiliation Centre Hospitalier Universitaire de Nice, Cancéropole PACA, Laboratoire de Pathologie Clinique et Expérimentale, Biobanque IRCAN, Inserm U1081, Nice, France
⨯
Caroline C. Mouline,

Affiliation Centre Hospitalier Universitaire de Nice, Unité de Thérapie Cellulaire et Génique, Nice, France
⨯
Wafa Khaali,

Affiliations Université Nice-Sophia Antipolis, UFR Médecine, ImCelVir URE004, Nice, France, Centre Hospitalier Universitaire de Nice, Unité de Thérapie Cellulaire et Génique, Nice, France
⨯
Yves Charbit,

Affiliations Université Nice-Sophia Antipolis, UFR Odontologie, LSBV URE001, Nice, France, Centre Hospitalier Universitaire de Nice, Pôle Odontologie, Hôpital Saint Roch, Nice, France
⨯
Patrick Mahler,

Affiliation Centre Hospitalier Universitaire de Nice, Pôle Odontologie, Hôpital Saint Roch, Nice, France
⨯
Isabelle Prêcheur,

Affiliations Université Nice-Sophia Antipolis, UFR Odontologie, LSBV URE001, Nice, France, Centre Hospitalier Universitaire de Nice, Pôle Odontologie, Hôpital Saint Roch, Nice, France
⨯
Paul Hofman,

Affiliation Centre Hospitalier Universitaire de Nice, Cancéropole PACA, Laboratoire de Pathologie Clinique et Expérimentale, Biobanque IRCAN, Inserm U1081, Nice, France
⨯
Janet L. Maryanski,

Affiliations Université Nice-Sophia Antipolis, UFR Médecine, ImCelVir URE004, Nice, France, Centre Hospitalier Universitaire de Nice, Unité de Thérapie Cellulaire et Génique, Nice, France, INSERM, UMR 576, F-06202 Nice, France
⨯
Alain Doglio

* E-mail: doglio@unice.fr

Affiliations Université Nice-Sophia Antipolis, UFR Médecine, ImCelVir URE004, Nice, France, Centre Hospitalier Universitaire de Nice, Unité de Thérapie Cellulaire et Génique, Nice, France
⨯

EBV Infection Is Common in Gingival Epithelial Cells of the Periodontium and Worsens during Chronic Periodontitis

Séverine Vincent-Bugnas,
Sébastien Vitale,
Caroline C. Mouline,
Wafa Khaali,
Yves Charbit,
Patrick Mahler,
Isabelle Prêcheur,
Paul Hofman,
Janet L. Maryanski,
Alain Doglio

Published: December 19, 2013
https://doi.org/10.1371/journal.pone.0080336

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Epithelial cells
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Apoptosis
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Epithelium
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Epstein-Barr virus
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Cell staining
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B cells
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Periodontitis
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Reverse transcriptase-polymerase chain reaction
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