Combining Biochemical and Imaging Markers to Improve Diagnosis and Characterization of Mild Traumatic Brain Injury in the Acute Setting: Results from a Pilot Study

Zhifeng Kou; Ramtilak Gattu; Firas Kobeissy; Robert D. Welch; Brian J. O’Neil; John L. Woodard; Syed Imran Ayaz; Andrew Kulek; Robert Kas-Shamoun; Valerie Mika; Conor Zuk; Francesco Tomasello; Stefania Mondello

doi:10.1371/journal.pone.0080296

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Open Access

Peer-reviewed

Research Article

Combining Biochemical and Imaging Markers to Improve Diagnosis and Characterization of Mild Traumatic Brain Injury in the Acute Setting: Results from a Pilot Study

Zhifeng Kou ,

* E-mail: zhifeng_kou@wayne.edu

Affiliations Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, United States of America, Department of Radiology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Ramtilak Gattu,

Affiliation Department of Radiology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Firas Kobeissy,

Affiliation Center for Neuroproteomics and Biomarkers Research, Department of Psychiatry, McKnight Brain Institute, University of Florida, Gainesville, Florida, United States of America
⨯
Robert D. Welch,

Affiliations Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America, Cardiovascular Research Institute, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Brian J. O’Neil,

Affiliations Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America, Cardiovascular Research Institute, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
John L. Woodard,

Affiliation Department of Psychology, Wayne State University, Detroit, Michigan, United States of America
⨯
Syed Imran Ayaz,

Affiliation Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Andrew Kulek,

Affiliation Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Robert Kas-Shamoun,

Affiliation Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Valerie Mika,

Affiliation Department of Emergency Medicine, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Conor Zuk,

Affiliation Department of Radiology, School of Medicine, Wayne State University, Detroit, Michigan, United States of America
⨯
Francesco Tomasello,

Affiliation Department of Neurosciences, University of Messina, Messina, Italy
⨯
Stefania Mondello

Affiliation Department of Neurosciences, University of Messina, Messina, Italy
⨯

Combining Biochemical and Imaging Markers to Improve Diagnosis and Characterization of Mild Traumatic Brain Injury in the Acute Setting: Results from a Pilot Study

Zhifeng Kou,
Ramtilak Gattu,
Firas Kobeissy,
Robert D. Welch,
Brian J. O’Neil,
John L. Woodard,
Syed Imran Ayaz,
Andrew Kulek,
Robert Kas-Shamoun,
Valerie Mika

Published: November 19, 2013
https://doi.org/10.1371/journal.pone.0080296

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