Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

Irina T. Zaharieva; Mattia Calissano; Mariacristina Scoto; Mark Preston; Sebahattin Cirak; Lucy Feng; James Collins; Ryszard Kole; Michela Guglieri; Volker Straub; Kate Bushby; Alessandra Ferlini; Jennifer E. Morgan; Francesco Muntoni

doi:10.1371/journal.pone.0080263

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Open Access

Peer-reviewed

Research Article

Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

Irina T. Zaharieva,

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯
Mattia Calissano,

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯
Mariacristina Scoto,

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯
Mark Preston,

Affiliation Department of Pathogen Molecular Biology, London School of Hygiene and Tropical Medicine, London, United Kingdom
⨯
Sebahattin Cirak,

Affiliations The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom, Childrens National Medical Centre, Research Centre for Genetic Medicine, Washington DC, United States of America
⨯
Lucy Feng,

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯
James Collins,

Affiliation Department of Pediatric Neurology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America
⨯
Ryszard Kole,

Affiliation Sarepta Therapeutics, Cambridge, Massachusetts, United States of America
⨯
Michela Guglieri,

Affiliation Institute of Human Genetics, Newcastle University, Newcastle, United Kingdom
⨯
Volker Straub,

Affiliation Institute of Human Genetics, Newcastle University, Newcastle, United Kingdom
⨯
Kate Bushby,

Affiliation Institute of Human Genetics, Newcastle University, Newcastle, United Kingdom
⨯
Alessandra Ferlini,

Affiliation Department of Medical Science, University of Ferrara, Ferrara, Italy
⨯
Jennifer E. Morgan,

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯
Francesco Muntoni

* E-mail: f.muntoni@ucl.ac.uk

Affiliation The Dubowitz Neuromuscular Centre, Institute of Child Health, University College London, London, United Kingdom
⨯

Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

Irina T. Zaharieva,
Mattia Calissano,
Mariacristina Scoto,
Mark Preston,
Sebahattin Cirak,
Lucy Feng,
James Collins,
Ryszard Kole,
Michela Guglieri,
Volker Straub

Published: November 25, 2013
https://doi.org/10.1371/journal.pone.0080263

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MicroRNAs
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Dystrophin
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Muscular dystrophies
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Duchenne muscular dystrophy
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Skeletal muscles
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