Comparative Sequence, Structure and Redox Analyses of Klebsiella pneumoniae DsbA Show That Anti-Virulence Target DsbA Enzymes Fall into Distinct Classes

• Fabian Kurth,

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Kieran Rimmer,

  Affiliation Faculty of Pharmacy and Pharmaceutical Sciences, Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia

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• Lakshmanane Premkumar,

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Biswaranjan Mohanty,

  Affiliation Faculty of Pharmacy and Pharmaceutical Sciences, Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia

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• Wilko Duprez,

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Maria A. Halili,

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Stephen R. Shouldice,

  Current address: Janssen-Cilag Pty Ltd., Macquarie Park, New South Wales, Australia

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Begoña Heras,

  Current address: Institute for Molecular Science, Latrobe University, Melbourne, Victoria, Australia

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• David P. Fairlie,

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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• Martin J. Scanlon ,

  * E-mail: j.martin@imb.uq.edu.au (JLM); martin.scanlon@monash.edu (MJS)

  Affiliations Faculty of Pharmacy and Pharmaceutical Sciences, Medicinal Chemistry, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia, ARC Centre of Excellence for Coherent X-ray Science, Monash University, Parkville, Victoria, Australia

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• Jennifer L. Martin

  * E-mail: j.martin@imb.uq.edu.au (JLM); martin.scanlon@monash.edu (MJS)

  Affiliation Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

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