The Homeobox Gene MEIS1 Is Methylated in BRAFp.V600E Mutated Colon Tumors

Ashwin A. Dihal; Arnoud Boot; Eddy H. van Roon; Melanie Schrumpf; Arantza Fariña-Sarasqueta; Marta Fiocco; Eliane C. M. Zeestraten; Peter J. K. Kuppen; Hans Morreau; Tom van Wezel; Judith M. Boer

doi:10.1371/journal.pone.0079898

Loading metrics

Open Access

Peer-reviewed

Research Article

The Homeobox Gene MEIS1 Is Methylated in BRAF^p.V600E Mutated Colon Tumors

Ashwin A. Dihal,

Affiliation Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
⨯
Arnoud Boot,

Affiliations Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Eddy H. van Roon,

Affiliations Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Melanie Schrumpf,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Arantza Fariña-Sarasqueta,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Marta Fiocco,

Affiliation Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands
⨯
Eliane C. M. Zeestraten,

Affiliation Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands
⨯
Peter J. K. Kuppen,

Affiliation Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands
⨯
Hans Morreau,

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Tom van Wezel ,

* E-mail: t.van_wezel@lumc.nl (TvW) j.m.boer@erasmusmc.nl (JMB)

Affiliation Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
⨯
Judith M. Boer

* E-mail: t.van_wezel@lumc.nl (TvW) j.m.boer@erasmusmc.nl (JMB)

Affiliations Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands, Department of Pediatric Oncology, Erasmus MC, Sophia Children’s Hospital, Rotterdam, The Netherlands, Netherlands Bioinformatics Center, Nijmegen, The Netherlands
⨯

The Homeobox Gene MEIS1 Is Methylated in BRAF^p.V600E Mutated Colon Tumors

Ashwin A. Dihal,
Arnoud Boot,
Eddy H. van Roon,
Melanie Schrumpf,
Arantza Fariña-Sarasqueta,
Marta Fiocco,
Eliane C. M. Zeestraten,
Peter J. K. Kuppen,
Hans Morreau,
Tom van Wezel

Published: November 7, 2013
https://doi.org/10.1371/journal.pone.0079898

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA methylation
Is the Subject Area "DNA methylation" applicable to this article?

Thanks for your feedback.
Colorectal cancer
Is the Subject Area "Colorectal cancer" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Colon
Is the Subject Area "Colon" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Breast cancer
Is the Subject Area "Breast cancer" applicable to this article?

Thanks for your feedback.
Methylation
Is the Subject Area "Methylation" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.