Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients

Song Xu; Gaia Cecilia Santini; Kim De Veirman; Isabelle Vande Broek; Xavier Leleu; Ann De Becker; Ben Van Camp; Karin Vanderkerken; Ivan Van Riet

doi:10.1371/journal.pone.0079752

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Peer-reviewed

Research Article

Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients

Song Xu ,

Contributed equally to this work with: Song Xu, Gaia Cecilia Santini

Affiliations Department of Lung Cancer Surgery, Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, P.R.China, Stem Cell Laboratory-Division Clinical Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium, Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
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Gaia Cecilia Santini ,

Contributed equally to this work with: Song Xu, Gaia Cecilia Santini

Affiliation Stem Cell Laboratory-Division Clinical Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium
⨯
Kim De Veirman,

Affiliations Stem Cell Laboratory-Division Clinical Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium, Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
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Isabelle Vande Broek,

Affiliation Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
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Xavier Leleu,

Affiliation Service d'Hématologie, Centre Hospitalier Universitaire (CHU), Lille, France
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Ann De Becker,

Affiliation Stem Cell Laboratory-Division Clinical Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium
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Ben Van Camp,

Affiliation Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
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Karin Vanderkerken,

Affiliation Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
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Ivan Van Riet

* E-mail: ivan.vanriet@uzbrussel.be

Affiliations Stem Cell Laboratory-Division Clinical Hematology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium, Department of Hematology and Immunology-Vrije Universiteit Brussel (VUB), Myeloma Center Brussels, Brussels, Belgium
⨯

Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients

Song Xu,
Gaia Cecilia Santini,
Kim De Veirman,
Isabelle Vande Broek,
Xavier Leleu,
Ann De Becker,
Ben Van Camp,
Karin Vanderkerken,
Ivan Van Riet

Published: November 6, 2013
https://doi.org/10.1371/journal.pone.0079752

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MicroRNAs
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Transfection
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Multiple myeloma
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