CYP2B6 Non-Coding Variation Associated with Smoking Cessation Is Also Associated with Differences in Allelic Expression, Splicing, and Nicotine Metabolism Independent of Common Amino-Acid Changes

• A. Joseph Bloom ,

  * E-mail: bloomj@psychiatry.wustl.edu

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Maribel Martinez,

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Li-Shiun Chen,

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Laura J. Bierut,

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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• Sharon E. Murphy,

  Affiliation Department of Biochemistry Molecular Biology and BioPhysics, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Alison Goate

  Affiliation Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, United States of America

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