Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

Gabriel Fung; Chen Seng Ng; Jingchun Zhang; Junyan Shi; Jerry Wong; Paulina Piesik; Lillian Han; Fanny Chu; Julienne Jagdeo; Eric Jan; Takashi Fujita; Honglin Luo

doi:10.1371/journal.pone.0079546

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Open Access

Peer-reviewed

Research Article

Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

Gabriel Fung,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Chen Seng Ng,

Affiliations Laboratory of Molecular Genetics, Institute of Virus Research, Kyoto University, Kyoto, Japan, Laboratory of Molecular Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan
⨯
Jingchun Zhang,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Junyan Shi,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Jerry Wong,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Paulina Piesik,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Lillian Han,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Fanny Chu,

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯
Julienne Jagdeo,

Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Eric Jan,

Affiliation Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Takashi Fujita,

Affiliations Laboratory of Molecular Genetics, Institute of Virus Research, Kyoto University, Kyoto, Japan, Laboratory of Molecular Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan
⨯
Honglin Luo

* E-mail: honglin.luo@hli.ubc.ca

Affiliation Department of Pathology and Laboratory Medicine, University of British Columbia, James Hogg Research Center, Providence Heart+Lung Institute, St. Paul’s Hospital Vancouver, Vancouver, British Columbia, Canada
⨯

Production of a Dominant-Negative Fragment Due to G3BP1 Cleavage Contributes to the Disruption of Mitochondria-Associated Protective Stress Granules during CVB3 Infection

Gabriel Fung,
Chen Seng Ng,
Jingchun Zhang,
Junyan Shi,
Jerry Wong,
Paulina Piesik,
Lillian Han,
Fanny Chu,
Julienne Jagdeo,
Eric Jan

Published: November 18, 2013
https://doi.org/10.1371/journal.pone.0079546

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