A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

R. Mark Jones; Jessica A. Chichester; Vadim Mett; Jennifer Jaje; Stephen Tottey; Slobodanka Manceva; Louis J. Casta; Sandra K. Gibbs; Konstantin Musiychuk; Moneim Shamloul; Joey Norikane; Valentina Mett; Stephen J. Streatfield; Marga van de Vegte-Bolmer; Will Roeffen; Robert W. Sauerwein; Vidadi Yusibov

doi:10.1371/journal.pone.0079538

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Peer-reviewed

Research Article

A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

R. Mark Jones,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Jessica A. Chichester,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Vadim Mett,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Jennifer Jaje,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Stephen Tottey,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Slobodanka Manceva,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Louis J. Casta,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Sandra K. Gibbs,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Konstantin Musiychuk,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Moneim Shamloul,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Joey Norikane,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Valentina Mett,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Stephen J. Streatfield,

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
Marga van de Vegte-Bolmer,

Affiliation Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
⨯
Will Roeffen,

Affiliation Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
⨯
Robert W. Sauerwein,

Affiliation Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
⨯
[ ... ],
Vidadi Yusibov

* E-mail: vyusibov@fraunhofer-cmb.org

Affiliation Fraunhofer USA Center for Molecular Biotechnology, Newark, Delaware, United States of America
⨯
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A Plant-Produced Pfs25 VLP Malaria Vaccine Candidate Induces Persistent Transmission Blocking Antibodies against Plasmodium falciparum in Immunized Mice

R. Mark Jones,
Jessica A. Chichester,
Vadim Mett,
Jennifer Jaje,
Stephen Tottey,
Slobodanka Manceva,
Louis J. Casta,
Sandra K. Gibbs,
Konstantin Musiychuk,
Moneim Shamloul

Published: November 18, 2013
https://doi.org/10.1371/journal.pone.0079538

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