An Anthelmintic Drug, Pyrvinium Pamoate, Thwarts Fibrosis and Ameliorates Myocardial Contractile Dysfunction in a Mouse Model of Myocardial Infarction

Open Access

Peer-reviewed

Research Article

Motoaki Murakoshi,

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan
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Kyohei Saiki,

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan
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Kyoji Urayama,

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan
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Thomas N. Sato

* E-mail: island1005@bs.naist.jp

Affiliations Graduate School of Biological Sciences, Nara Institute of Science and Technology, Nara, Japan, Department of Biomedical Engineering, Cornell University, Ithaca, New York, United States of America, Centenary Institute, Sydney, Australia
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Fibroblasts
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Mouse models
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Fibrosis
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Heart
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Myocardial infarction
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Cardiomyocytes
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Glucose
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Oxygen
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