Crystal Structures of Trypanosoma brucei Oligopeptidase B Broaden the Paradigm of Catalytic Regulation in Prolyl Oligopeptidase Family Enzymes

Open Access

Peer-reviewed

Research Article

Peter Canning ,

Contributed equally to this work with: Peter Canning, Dean Rea

Current address: Structural Genomics Consortium, Old Road Campus Research Building, University of Oxford, Oxford, United Kingdom

Affiliation School of Life Sciences, University of Warwick, Coventry, United Kingdom
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Dean Rea ,

Contributed equally to this work with: Peter Canning, Dean Rea

Affiliation School of Life Sciences, University of Warwick, Coventry, United Kingdom
⨯
Rory E. Morty,

Affiliation Department of Lung Development and Remodelling, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany
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Vilmos Fülöp

* E-mail: V.Fulop@warwick.ac.uk

Affiliation School of Life Sciences, University of Warwick, Coventry, United Kingdom
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Crystal structure
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Enzyme structure
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Enzymes
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Dimers
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Electron density
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Hydrogen bonding
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Trypanosoma brucei gambiense
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Catalysis
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