Comparison of Mutation Patterns in Full-Genome A/H3N2 Influenza Sequences Obtained Directly from Clinical Samples and the Same Samples after a Single MDCK Passage

Hong Kai Lee; Julian Wei-Tze Tang; Debra Han-Lin Kong; Tze Ping Loh; Donald Kok-Leong Chiang; Tommy Tsan-Yuk Lam; Evelyn Siew-Chuan Koay

doi:10.1371/journal.pone.0079252

Loading metrics

Open Access

Peer-reviewed

Research Article

Comparison of Mutation Patterns in Full-Genome A/H3N2 Influenza Sequences Obtained Directly from Clinical Samples and the Same Samples after a Single MDCK Passage

Hong Kai Lee,

Affiliations Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Laboratory Medicine, National University Hospital, National University Health System, Singapore, Singapore
⨯
Julian Wei-Tze Tang ,

* E-mail: julian.tang@albertahealthservices.ca (JW-TT); evelyn_koay@nuhs.edu.sg (ES-CK)

Affiliations Alberta Provincial Laboratory for Public Health, University of Alberta Hospital, Edmonton, Canada, Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Canada
⨯
Debra Han-Lin Kong,

Affiliation Department of Laboratory Medicine, National University Hospital, National University Health System, Singapore, Singapore
⨯
Tze Ping Loh,

Affiliation Department of Laboratory Medicine, National University Hospital, National University Health System, Singapore, Singapore
⨯
Donald Kok-Leong Chiang,

Affiliation Department of Laboratory Medicine, National University Hospital, National University Health System, Singapore, Singapore
⨯
Tommy Tsan-Yuk Lam,

Affiliation Department of Zoology, University of Oxford, Oxford, United Kingdom
⨯
Evelyn Siew-Chuan Koay

* E-mail: julian.tang@albertahealthservices.ca (JW-TT); evelyn_koay@nuhs.edu.sg (ES-CK)

Affiliations Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Laboratory Medicine, National University Hospital, National University Health System, Singapore, Singapore
⨯

Comparison of Mutation Patterns in Full-Genome A/H3N2 Influenza Sequences Obtained Directly from Clinical Samples and the Same Samples after a Single MDCK Passage

Hong Kai Lee,
Julian Wei-Tze Tang,
Debra Han-Lin Kong,
Tze Ping Loh,
Donald Kok-Leong Chiang,
Tommy Tsan-Yuk Lam,
Evelyn Siew-Chuan Koay

Published: November 1, 2013
https://doi.org/10.1371/journal.pone.0079252

Reader Comments (1)

Post a new comment on this article

0 Responses

25 Sep 2019
02:59 GMT
Most Recent

Reference virus name need correction Posted by Lei.yang909 on 25 Sep 2019 at 02:59 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Influenza
Is the Subject Area "Influenza" applicable to this article?

Thanks for your feedback.
Microbial mutation
Is the Subject Area "Microbial mutation" applicable to this article?

Thanks for your feedback.
Influenza viruses
Is the Subject Area "Influenza viruses" applicable to this article?

Thanks for your feedback.
Mutation databases
Is the Subject Area "Mutation databases" applicable to this article?

Thanks for your feedback.
Kidneys
Is the Subject Area "Kidneys" applicable to this article?

Thanks for your feedback.
Viral replication
Is the Subject Area "Viral replication" applicable to this article?

Thanks for your feedback.
Mammalian genomics
Is the Subject Area "Mammalian genomics" applicable to this article?

Thanks for your feedback.
Viral load
Is the Subject Area "Viral load" applicable to this article?

Thanks for your feedback.