Proteomic Identification of Mitochondrial Targets of Arginase in Human Breast Cancer

Rajan Singh; Nuraly K. Avliyakulov; Melissa Braga; Michael J. Haykinson; Luis Martinez; Vikash Singh; Meher Parveen; Gautam Chaudhuri; Shehla Pervin

doi:10.1371/journal.pone.0079242

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Open Access

Peer-reviewed

Research Article

Proteomic Identification of Mitochondrial Targets of Arginase in Human Breast Cancer

Rajan Singh ,

* E-mail: rajansingh@mednet.ucla.edu

Affiliations Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯
Nuraly K. Avliyakulov,

Affiliation Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯
Melissa Braga,

Affiliation Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America
⨯
Michael J. Haykinson,

Affiliation Department of Biological Chemistry, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯
Luis Martinez,

Affiliation Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America
⨯
Vikash Singh,

Affiliation Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America
⨯
Meher Parveen,

Affiliation Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America
⨯
Gautam Chaudhuri,

Affiliations Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯
Shehla Pervin

Affiliations Internal Medicine, Charles Drew University of Medicine and Science, Los Angeles, California, United States of America, Department of Obstetrics and Gynecology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America
⨯

Proteomic Identification of Mitochondrial Targets of Arginase in Human Breast Cancer

Rajan Singh,
Nuraly K. Avliyakulov,
Melissa Braga,
Michael J. Haykinson,
Luis Martinez,
Vikash Singh,
Meher Parveen,
Gautam Chaudhuri,
Shehla Pervin

Published: November 5, 2013
https://doi.org/10.1371/journal.pone.0079242

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Breast cancer
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Mitochondria
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Protein expression
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Cancer treatment
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Breast tumors
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Apoptosis
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Gene expression
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Small interfering RNA
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