Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation

Cintia Roodveldt; Adahir Labrador-Garrido; Elena Gonzalez-Rey; Christian C. Lachaud; Tim Guilliams; Rafael Fernandez-Montesinos; Alicia Benitez-Rondan; Gema Robledo; Abdelkrim Hmadcha; Mario Delgado; Christopher M. Dobson; David Pozo

doi:10.1371/journal.pone.0079160

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Peer-reviewed

Research Article

Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation

Cintia Roodveldt ,

Contributed equally to this work with: Cintia Roodveldt, Adahir Labrador-Garrido

Affiliation CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain
⨯
Adahir Labrador-Garrido ,

Contributed equally to this work with: Cintia Roodveldt, Adahir Labrador-Garrido

Affiliations CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, University of Seville, Seville, Spain
⨯
Elena Gonzalez-Rey,

Affiliation Institute of Parasitology and Biomedicine ‘Lopez-Neyra’, CSIC, Granada, Spain
⨯
Christian C. Lachaud,

Affiliation CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain
⨯
Tim Guilliams,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
Rafael Fernandez-Montesinos,

Affiliations CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, University of Seville, Seville, Spain
⨯
Alicia Benitez-Rondan,

Affiliation CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain
⨯
Gema Robledo,

Affiliation Institute of Parasitology and Biomedicine ‘Lopez-Neyra’, CSIC, Granada, Spain
⨯
Abdelkrim Hmadcha,

Affiliation CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain
⨯
Mario Delgado,

Affiliation Institute of Parasitology and Biomedicine ‘Lopez-Neyra’, CSIC, Granada, Spain
⨯
Christopher M. Dobson,

Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom
⨯
David Pozo

* E-mail: david.pozo@cabimer.es

Affiliations CABIMER, Andalusian Center for Molecular Biology and Regenerative Medicine, Seville, Spain, Department of Medical Biochemistry, Molecular Biology and Immunology, School of Medicine, University of Seville, Seville, Spain
⨯

Preconditioning of Microglia by α-Synuclein Strongly Affects the Response Induced by Toll-like Receptor (TLR) Stimulation

Cintia Roodveldt,
Adahir Labrador-Garrido,
Elena Gonzalez-Rey,
Christian C. Lachaud,
Tim Guilliams,
Rafael Fernandez-Montesinos,
Alicia Benitez-Rondan,
Gema Robledo,
Abdelkrim Hmadcha,
Mario Delgado

Published: November 13, 2013
https://doi.org/10.1371/journal.pone.0079160

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