An Optimized Immunohistochemistry Technique Improves NMO-IgG Detection: Study Comparison with Cell-Based Assays

Romana Höftberger; Lidia Sabater; Romain Marignier; Fahmy Aboul-Enein; Raphaël Bernard-Valnet; Helmut Rauschka; Anne Ruiz; Yolanda Blanco; Francesc Graus; Josep Dalmau; Albert Saiz

doi:10.1371/journal.pone.0079083

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Peer-reviewed

Research Article

An Optimized Immunohistochemistry Technique Improves NMO-IgG Detection: Study Comparison with Cell-Based Assays

Romana Höftberger,

Affiliations Service of Neurology, Hospital Clínic, Universitat de Barcelona and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain, Institute of Neurology, Medical University of Vienna, Vienna, Austria
⨯
Lidia Sabater,

Affiliation Service of Neurology, Hospital Clínic, Universitat de Barcelona and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Romain Marignier,

Affiliation Team ONCOFLAM, Lyon Neuroscience Research Center INSERM U 1028/CNRS 5292, Lyon, France
⨯
Fahmy Aboul-Enein,

Affiliation Department of Neurology, SMZ-Ost Donauspital, Vienna, Austria
⨯
Raphaël Bernard-Valnet,

Affiliation Team ONCOFLAM, Lyon Neuroscience Research Center INSERM U 1028/CNRS 5292, Lyon, France
⨯
Helmut Rauschka,

Affiliation Department of Neurology, SMZ-Ost Donauspital, Vienna, Austria
⨯
Anne Ruiz,

Affiliation Team ONCOFLAM, Lyon Neuroscience Research Center INSERM U 1028/CNRS 5292, Lyon, France
⨯
Yolanda Blanco,

Affiliation Service of Neurology, Hospital Clínic, Universitat de Barcelona and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Francesc Graus,

Affiliation Service of Neurology, Hospital Clínic, Universitat de Barcelona and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯
Josep Dalmau,

Affiliations Institució Catalana de Recerca i Estudis Avançats (ICREA), IDIBAPS, Hospital Clínic, Barcelona, Spain, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Albert Saiz

* E-mail: asaiz@clinic.ub.es

Affiliation Service of Neurology, Hospital Clínic, Universitat de Barcelona and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⨯

An Optimized Immunohistochemistry Technique Improves NMO-IgG Detection: Study Comparison with Cell-Based Assays

Romana Höftberger,
Lidia Sabater,
Romain Marignier,
Fahmy Aboul-Enein,
Raphaël Bernard-Valnet,
Helmut Rauschka,
Anne Ruiz,
Yolanda Blanco,
Francesc Graus,
Josep Dalmau

Published: November 4, 2013
https://doi.org/10.1371/journal.pone.0079083

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