Enhancing the Function of CD34+ Cells by Targeting Plasminogen Activator Inhibitor-1

Sugata Hazra; Valerie Stepps; Ashay D. Bhatwadekar; Sergio Caballero; Michael E. Boulton; Paul J. Higgins; Elena V. Nikonova; Carl J. Pepine; Catherine Thut; Eva M. Finney; David J. Stone; Stephen H. Bartelmez; Maria B. Grant

doi:10.1371/journal.pone.0079067

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Open Access

Peer-reviewed

Research Article

Enhancing the Function of CD34⁺ Cells by Targeting Plasminogen Activator Inhibitor-1

Sugata Hazra,

Affiliation Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, United States of America
⨯
Valerie Stepps,

Affiliation BetaStem Therapeutics, Inc, San Francisco, California, United States of America
⨯
Ashay D. Bhatwadekar,

Affiliation Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, United States of America
⨯
Sergio Caballero,

Affiliation Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, United States of America
⨯
Michael E. Boulton,

Affiliation Department of Anatomy and Cell Biology, University of Florida, Gainesville, Florida, United States of America
⨯
Paul J. Higgins,

Affiliation Center for Cell Biology and Cancer Research, Albany Medical College, Albany, New York, United States of America
⨯
Elena V. Nikonova,

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck & Co. Inc,West Point, Pennsylvania., United States of America
⨯
Carl J. Pepine,

Affiliation Department of Medicine, University of Florida, Gainesville, Florida, United States of America
⨯
Catherine Thut,

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck & Co. Inc,West Point, Pennsylvania., United States of America
⨯
Eva M. Finney,

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck & Co. Inc,West Point, Pennsylvania., United States of America
⨯
David J. Stone,

Affiliation Exploratory and Translational Sciences, Merck Research Laboratories, Merck & Co. Inc,West Point, Pennsylvania., United States of America
⨯
Stephen H. Bartelmez,

Affiliation BetaStem Therapeutics, Inc, San Francisco, California, United States of America
⨯
Maria B. Grant

* E-mail: grantma@ufl.edu

Affiliation Department of Pharmacology and Therapeutics, University of Florida, Gainesville, Florida, United States of America
⨯

Enhancing the Function of CD34⁺ Cells by Targeting Plasminogen Activator Inhibitor-1

Sugata Hazra,
Valerie Stepps,
Ashay D. Bhatwadekar,
Sergio Caballero,
Michael E. Boulton,
Paul J. Higgins,
Elena V. Nikonova,
Carl J. Pepine,
Catherine Thut,
Eva M. Finney

Published: November 1, 2013
https://doi.org/10.1371/journal.pone.0079067

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