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Open Access
Peer-reviewed
Research Article
Downregulation of IFNG in CD4+ T Cells in Lung Cancer through Hypermethylation: A Possible Mechanism of Tumor-Induced Immunosuppression
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Fang Wang ,
Contributed equally to this work with: Fang Wang, Jian Xu, Quan Zhu
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Jian Xu ,
Contributed equally to this work with: Fang Wang, Jian Xu, Quan Zhu
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Quan Zhu ,
Contributed equally to this work with: Fang Wang, Jian Xu, Quan Zhu
Affiliation Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xuejun Qin,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Yan Cao,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Jiangfang Lou,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Yuqiao Xu,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Xing Ke,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Qing Li,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Erfu Xie,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Lixia Zhang,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Ruihong Sun,
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Liang Chen,
Affiliation Department of Cardiothoracic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Bingliang Fang,
Affiliation Department of Thoracic and Cardiovascular Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Shiyang Pan
* E-mail: sypan@njmu.edu.cn
Affiliations Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China, National Key Clinical Department of Laboratory Medicine, Nanjing, China
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Downregulation of IFNG in CD4+ T Cells in Lung Cancer through Hypermethylation: A Possible Mechanism of Tumor-Induced Immunosuppression
- Fang Wang,
- Jian Xu,
- Quan Zhu,
- Xuejun Qin,
- Yan Cao,
- Jiangfang Lou,
- Yuqiao Xu,
- Xing Ke,
- Qing Li,
- Erfu Xie
- Published: November 11, 2013
- https://doi.org/10.1371/journal.pone.0079064