A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

David Gaviria; Michelle F. Paguio; Lindsey B. Turnbull; Asako Tan; Amila Siriwardana; Debasish Ghosh; Michael T. Ferdig; Anthony P. Sinai; Paul D. Roepe

doi:10.1371/journal.pone.0079059

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Peer-reviewed

Research Article

A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

David Gaviria,

Affiliation Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, District of Columbia, United States of America
⨯
Michelle F. Paguio,

Affiliation Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, District of Columbia, United States of America
⨯
Lindsey B. Turnbull,

Affiliation Eck Institute for Global Health, Department of Biology, University of Notre Dame, Notre Dame, Indiana, United States of America
⨯
Asako Tan,

Affiliation Eck Institute for Global Health, Department of Biology, University of Notre Dame, Notre Dame, Indiana, United States of America
⨯
Amila Siriwardana,

Affiliation Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, District of Columbia, United States of America
⨯
Debasish Ghosh,

Affiliation Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Michael T. Ferdig,

Affiliation Eck Institute for Global Health, Department of Biology, University of Notre Dame, Notre Dame, Indiana, United States of America
⨯
Anthony P. Sinai,

Affiliation Department of Microbiology, Immunology and Molecular Genetics, University of Kentucky College of Medicine, Lexington, Kentucky, United States of America
⨯
Paul D. Roepe

* E-mail: roepep@georgetown.edu

Affiliation Departments of Chemistry and of Biochemistry, Cellular and Molecular Biology, Georgetown University, Washington, District of Columbia, United States of America
⨯

A Process Similar to Autophagy Is Associated with Cytocidal Chloroquine Resistance in Plasmodium falciparum

David Gaviria,
Michelle F. Paguio,
Lindsey B. Turnbull,
Asako Tan,
Amila Siriwardana,
Debasish Ghosh,
Michael T. Ferdig,
Anthony P. Sinai,
Paul D. Roepe

Published: November 20, 2013
https://doi.org/10.1371/journal.pone.0079059

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Autophagic cell death
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Plasmodium
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