Overexpressing STAMP2 Improves Insulin Resistance in Diabetic ApoE−/−/LDLR−/− Mice via Macrophage Polarization Shift in Adipose Tissues

Lu Han; Meng-Xiong Tang; Yun Ti; Zhi-Hao Wang; Jia Wang; Wen-Yuan Ding; Hua Wang; Yun Zhang; Wei Zhang; Ming Zhong

doi:10.1371/journal.pone.0078903

Loading metrics

Open Access

Peer-reviewed

Research Article

Overexpressing STAMP2 Improves Insulin Resistance in Diabetic ApoE^−/−/LDLR^−/− Mice via Macrophage Polarization Shift in Adipose Tissues

Lu Han,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Meng-Xiong Tang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Emergency, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Yun Ti,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Zhi-Hao Wang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Geriatric Medicine, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Jia Wang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Wen-Yuan Ding,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Hua Wang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Yun Zhang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Wei Zhang,

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯
Ming Zhong

* E-mail: zhongmingzm@gmail.com.

Affiliations Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health, Ji’nan, People’s Republic of China, Department of Cardiology, Qilu Hospital of Shandong University, Ji’nan, People’s Republic of China
⨯

Overexpressing STAMP2 Improves Insulin Resistance in Diabetic ApoE^−/−/LDLR^−/− Mice via Macrophage Polarization Shift in Adipose Tissues

Lu Han,
Meng-Xiong Tang,
Yun Ti,
Zhi-Hao Wang,
Jia Wang,
Wen-Yuan Ding,
Hua Wang,
Yun Zhang,
Wei Zhang,
Ming Zhong

Published: November 13, 2013
https://doi.org/10.1371/journal.pone.0078903

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Brown adipose tissue
Is the Subject Area "Brown adipose tissue" applicable to this article?

Thanks for your feedback.
Macrophages
Is the Subject Area "Macrophages" applicable to this article?

Thanks for your feedback.
Insulin resistance
Is the Subject Area "Insulin resistance" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Inflammation
Is the Subject Area "Inflammation" applicable to this article?

Thanks for your feedback.
Adipocytes
Is the Subject Area "Adipocytes" applicable to this article?

Thanks for your feedback.
Cytokines
Is the Subject Area "Cytokines" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.