Erlotinib Inhibits Growth of a Patient-Derived Chordoma Xenograft

I-Mei Siu; Jacob Ruzevick; Qi Zhao; Nick Connis; Yuchen Jiao; Chetan Bettegowda; Xuewei Xia; Peter C. Burger; Christine L. Hann; Gary L. Gallia

doi:10.1371/journal.pone.0078895

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Open Access

Peer-reviewed

Research Article

Erlotinib Inhibits Growth of a Patient-Derived Chordoma Xenograft

I-Mei Siu,

Affiliation Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Jacob Ruzevick,

Affiliation Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Qi Zhao,

Affiliations Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Ludwig Collaborative Laboratory, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Nick Connis,

Affiliation Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Yuchen Jiao,

Affiliation Ludwig Center for Cancer Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Chetan Bettegowda,

Affiliations Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Ludwig Center for Cancer Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Xuewei Xia,

Affiliations Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Neurosurgery, Affiliated Hospital of Gulin Medical College, Guilin, China
⨯
Peter C. Burger,

Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Christine L. Hann,

Affiliation Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Gary L. Gallia

* E-mail: ggallia1@jhmi.edu

Affiliations Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯

Erlotinib Inhibits Growth of a Patient-Derived Chordoma Xenograft

I-Mei Siu,
Jacob Ruzevick,
Qi Zhao,
Nick Connis,
Yuchen Jiao,
Chetan Bettegowda,
Xuewei Xia,
Peter C. Burger,
Christine L. Hann,
Gary L. Gallia

Published: November 15, 2013
https://doi.org/10.1371/journal.pone.0078895

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