HER2 Phosphorylates and Destabilizes Pro-Apoptotic PUMA, Leading to Antagonized Apoptosis in Cancer Cells

Open Access

Peer-reviewed

Research Article

Richard L. Carpenter,

Affiliation Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, North Carolina, United States of America
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Woody Han,

Affiliation Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, North Carolina, United States of America
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Ivy Paw,

Affiliation Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, North Carolina, United States of America
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Hui-Wen Lo

* E-mail: huiwen.lo@duke.edu

Affiliations Division of Surgical Sciences, Department of Surgery, Duke University School of Medicine, Durham, North Carolina, United States of America, Duke Cancer Institute, Duke University School of Medicine, Durham, North Carolina, United States of America, Duke Center for RNA Biology, Duke University School of Medicine, Durham, North Carolina, United States of America
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Phosphorylation
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Apoptosis
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Tyrosine
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Immunoprecipitation
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Breast cancer
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Immunoblotting
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Mitochondria
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Transfection
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