Potent Anti-Diabetic Effects of MHY908, a Newly Synthesized PPAR α/γ Dual Agonist in db/db Mice

Min Hi Park; Ji Young Park; Hye Jin Lee; Dae Hyun Kim; Daeui Park; Hyoung Oh Jeong; Chan Hum Park; Pusoon Chun; Hyung Ryong Moon; Hae Young Chung

doi:10.1371/journal.pone.0078815

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Peer-reviewed

Research Article

Potent Anti-Diabetic Effects of MHY908, a Newly Synthesized PPAR α/γ Dual Agonist in db/db Mice

Min Hi Park,

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯
Ji Young Park,

Affiliation Laboratory of Medicinal Chemistry, College of Pharmacy, Pusan National University, Busan, Korea
⨯
Hye Jin Lee,

Affiliation Laboratory of Medicinal Chemistry, College of Pharmacy, Pusan National University, Busan, Korea
⨯
Dae Hyun Kim,

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯
Daeui Park,

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯
Hyoung Oh Jeong,

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯
Chan Hum Park,

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯
Pusoon Chun,

Affiliation College of Pharmacy, Inje University, Gimhae, Gyeongnam, Korea
⨯
Hyung Ryong Moon ,

* E-mail: hyjung@pusan.ac.kr (HYC); mhr108@pusan.ac.kr (HRM)

Affiliation Laboratory of Medicinal Chemistry, College of Pharmacy, Pusan National University, Busan, Korea
⨯
Hae Young Chung

* E-mail: hyjung@pusan.ac.kr (HYC); mhr108@pusan.ac.kr (HRM)

Affiliations Molecular Inflammation Research Center for Aging intervention (MRCA), College of Pharmacy, Pusan National University, Busan, Korea, Laboratory of Biochemistry, Pusan National University, Busan, Korea
⨯

Potent Anti-Diabetic Effects of MHY908, a Newly Synthesized PPAR α/γ Dual Agonist in db/db Mice

Min Hi Park,
Ji Young Park,
Hye Jin Lee,
Dae Hyun Kim,
Daeui Park,
Hyoung Oh Jeong,
Chan Hum Park,
Pusoon Chun,
Hyung Ryong Moon,
Hae Young Chung

Published: November 14, 2013
https://doi.org/10.1371/journal.pone.0078815

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