The Effect of Factor VIII Deficiencies and Replacement and Bypass Therapies on Thrombus Formation under Venous Flow Conditions in Microfluidic and Computational Models

• Abimbola A. Onasoga-Jarvis,

  Affiliation Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, Colorado, United States of America

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• Karin Leiderman,

  Affiliation Applied Math Unit, School of Natural Sciences, University of California Merced, Merced, California, United States of America

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• Aaron L. Fogelson,

  Affiliation Department of Mathematics and Department of Bioengineering, University of Utah, Salt Lake City, Utah, United States of America

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• Michael Wang,

  Affiliation Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado Denver, Aurora, Colorado, United States of America

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• Marilyn J. Manco-Johnson,

  Affiliation Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado Denver, Aurora, Colorado, United States of America

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• Jorge A. Di Paola,

  Affiliation Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado Denver, Aurora, Colorado, United States of America

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• Keith B. Neeves

  * E-mail: kneeves@mines.edu

  Affiliations Department of Chemical and Biological Engineering, Colorado School of Mines, Golden, Colorado, United States of America, Department of Pediatrics, Hemophilia and Thrombosis Center, University of Colorado Denver, Aurora, Colorado, United States of America

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