Proteasomal Degradation of Mcl-1 by Maritoclax Induces Apoptosis and Enhances the Efficacy of ABT-737 in Melanoma Cells

Open Access

Peer-reviewed

Research Article

Manoj K. Pandey ,

Contributed equally to this work with: Manoj K. Pandey, Krishne Gowda

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Krishne Gowda ,

Contributed equally to this work with: Manoj K. Pandey, Krishne Gowda

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Kenichiro Doi,

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Arun K. Sharma,

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Hong-Gang Wang ,

* E-mail: sga3@psu.edu (SA); huw11@psu.edu (HGW)

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯
Shantu Amin

* E-mail: sga3@psu.edu (SA); huw11@psu.edu (HGW)

Affiliation Department of Pharmacology, Penn State College of Medicine, Hershey, Pennsylvania, United States of America
⨯

Reader Comments (0)

Melanoma cells
Is the Subject Area "Melanoma cells" applicable to this article?

Thanks for your feedback.
Melanoma
Is the Subject Area "Melanoma" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Cytoskeleton
Is the Subject Area "Cytoskeleton" applicable to this article?

Thanks for your feedback.
Cell staining
Is the Subject Area "Cell staining" applicable to this article?

Thanks for your feedback.
Cell signaling
Is the Subject Area "Cell signaling" applicable to this article?

Thanks for your feedback.
Small cell lung cancer
Is the Subject Area "Small cell lung cancer" applicable to this article?

Thanks for your feedback.