Stability of Transmembrane Amyloid β-Peptide and Membrane Integrity Tested by Molecular Modeling of Site-Specific Aβ42 Mutations

Open Access

Peer-reviewed

Research Article

Stability of Transmembrane Amyloid β-Peptide and Membrane Integrity Tested by Molecular Modeling of Site-Specific Aβ₄₂ Mutations

Chetan Poojari,

Affiliation Institute of Complex Systems: Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany
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Birgit Strodel

* E-mail: b.strodel@fz-juelich.de

Affiliations Institute of Complex Systems: Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany, Institute of Theoretical and Computational Chemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
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Lipids
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Monomers
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Biochemical simulations
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Cell membranes
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Lipid bilayer
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Oligomers
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Point mutation
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Salt bridges
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