Alternative Signaling Pathways as Potential Therapeutic Targets for Overcoming EGFR and c-Met Inhibitor Resistance in Non-Small Cell Lung Cancer

Open Access

Peer-reviewed

Research Article

Jason T. Fong ,

Contributed equally to this work with: Jason T. Fong, Neelu Puri

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
⨯
Ryan J. Jacobs,

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
⨯
David N. Moravec,

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
⨯
Srijayaprakash B. Uppada,

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
⨯
Gregory M. Botting,

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
⨯
Marie Nlend,

Affiliation Thermo Fisher Scientific, Rockford, Illinois, United States of America
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Neelu Puri

Contributed equally to this work with: Jason T. Fong, Neelu Puri

* E-mail: neelupur@uic.edu

Affiliation Department of Biomedical Sciences, University of Illinois College of Medicine, Rockford, Illinois, United States
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Non-small cell lung cancer
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Wnt signaling cascade
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MTT assay
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Phosphorylation
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EGFR signaling
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Signal inhibition
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Cloning
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Protease inhibitor therapy
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