Analysis of Serum Inflammatory Mediators Identifies Unique Dynamic Networks Associated with Death and Spontaneous Survival in Pediatric Acute Liver Failure

Nabil Azhar; Cordelia Ziraldo; Derek Barclay; David A. Rudnick; Robert H. Squires; Yoram Vodovotz; for the Pediatric Acute Liver Failure Study Group

doi:10.1371/journal.pone.0078202

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Peer-reviewed

Research Article

Analysis of Serum Inflammatory Mediators Identifies Unique Dynamic Networks Associated with Death and Spontaneous Survival in Pediatric Acute Liver Failure

Nabil Azhar ,

Contributed equally to this work with: Nabil Azhar, Cordelia Ziraldo

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Cordelia Ziraldo ,

Contributed equally to this work with: Nabil Azhar, Cordelia Ziraldo

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Derek Barclay,

Affiliation Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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David A. Rudnick,

Affiliation Department of Pediatrics, Washington University of St. Louis, St. Louis, Missouri, United States of America
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Robert H. Squires,

Affiliation Department of Pediatrics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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Yoram Vodovotz ,

* E-mail: vodovotzy@upmc.edu

Affiliations Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Center for Inflammation and Regenerative Modeling, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
for the Pediatric Acute Liver Failure Study Group

Analysis of Serum Inflammatory Mediators Identifies Unique Dynamic Networks Associated with Death and Spontaneous Survival in Pediatric Acute Liver Failure

Nabil Azhar,
Cordelia Ziraldo,
Derek Barclay,
David A. Rudnick,
Robert H. Squires,
Yoram Vodovotz,
for the Pediatric Acute Liver Failure Study Group

Published: November 11, 2013
https://doi.org/10.1371/journal.pone.0078202

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Inflammation
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