Positive Selection in Bone Morphogenetic Protein 15 Targets a Natural Mutation Associated with Primary Ovarian Insufficiency in Human

Sylvain Auclair; Raffaella Rossetti; Camille Meslin; Olivier Monestier; Elisa Di Pasquale; Géraldine Pascal; Luca Persani; Stéphane Fabre

doi:10.1371/journal.pone.0078199

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Peer-reviewed

Research Article

Positive Selection in Bone Morphogenetic Protein 15 Targets a Natural Mutation Associated with Primary Ovarian Insufficiency in Human

Sylvain Auclair ,

Contributed equally to this work with: Sylvain Auclair, Raffaella Rossetti

Affiliations INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France, CNRS, UMR7247 Physiologie de la Reproduction et des Comportements, Nouzilly, France, Université François Rabelais de Tours, Tours, France, IFCE, Nouzilly, France
⨯
Raffaella Rossetti ,

Contributed equally to this work with: Sylvain Auclair, Raffaella Rossetti

Affiliation Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
⨯
Camille Meslin,

Affiliations INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France, CNRS, UMR7247 Physiologie de la Reproduction et des Comportements, Nouzilly, France, Université François Rabelais de Tours, Tours, France, IFCE, Nouzilly, France
⨯
Olivier Monestier,

Affiliation INRA-ENVT, UMR 444, Laboratoire de Génétique Cellulaire, Castanet-Tolosan, France
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Elisa Di Pasquale,

Affiliation Institute of Genetic and Biomedical Research - UOS of Milan, National Research Council of Italy, Istituto Clinico Humanitas, Milan, Italy
⨯
Géraldine Pascal,

Affiliations INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France, CNRS, UMR7247 Physiologie de la Reproduction et des Comportements, Nouzilly, France, Université François Rabelais de Tours, Tours, France, IFCE, Nouzilly, France
⨯
Luca Persani,

Affiliations Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, Laboratorio di Ricerche Endocrino-Metaboliche, Istituto Auxologico Italiano, Milan, Italy
⨯
Stéphane Fabre

* E-mail: stephane.fabre@tours.inra.fr

Affiliations INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France, CNRS, UMR7247 Physiologie de la Reproduction et des Comportements, Nouzilly, France, Université François Rabelais de Tours, Tours, France, IFCE, Nouzilly, France, INRA-ENVT, UMR 444, Laboratoire de Génétique Cellulaire, Castanet-Tolosan, France
⨯

Positive Selection in Bone Morphogenetic Protein 15 Targets a Natural Mutation Associated with Primary Ovarian Insufficiency in Human

Sylvain Auclair,
Raffaella Rossetti,
Camille Meslin,
Olivier Monestier,
Elisa Di Pasquale,
Géraldine Pascal,
Luca Persani,
Stéphane Fabre

Published: October 16, 2013
https://doi.org/10.1371/journal.pone.0078199

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