Preferential Activation of the Hedgehog Pathway by Epigenetic Modulations in HPV Negative HNSCC Identified with Meta-Pathway Analysis

• Elana J. Fertig ,

  * E-mail: ejfertig@jhmi.edu

  Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Ana Markovic,

  Affiliation Department of Hematopoietic Malignancies, Hellen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, California, United States of America

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• Ludmila V. Danilova,

  Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Daria A. Gaykalova,

  Affiliation Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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• Leslie Cope,

  Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Christine H. Chung,

  Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Michael F. Ochs,

  Affiliations Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Health Science Informatics, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

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• Joseph A. Califano

  Affiliations Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America, Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America

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