Reduction of the CD16−CD56bright NK Cell Subset Precedes NK Cell Dysfunction in Prostate Cancer

Kyo Chul Koo; Doo Hee Shim; Chang Mo Yang; Saet-Byul Lee; Shi Mun Kim; Tae Young Shin; Kwang Hyun Kim; Ho Geun Yoon; Koon Ho Rha; Jae Myun Lee; Sung Joon Hong

doi:10.1371/journal.pone.0078049

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Open Access

Peer-reviewed

Research Article

Reduction of the CD16⁻CD56^bright NK Cell Subset Precedes NK Cell Dysfunction in Prostate Cancer

Kyo Chul Koo,

Affiliation Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Doo Hee Shim,

Affiliation Department of Microbiology, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Chang Mo Yang,

Affiliations Department of Microbiology, Yonsei University College of Medicine, Seoul, Republic of Korea, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Saet-Byul Lee,

Affiliations Department of Microbiology, Yonsei University College of Medicine, Seoul, Republic of Korea, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Shi Mun Kim,

Affiliation ATgen, Sungnam, Republic of Korea
⨯
Tae Young Shin,

Affiliation Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Kwang Hyun Kim,

Affiliation Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Ho Geun Yoon,

Affiliations Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea, Department of Biochemistry and Molecular Biology, Severance Medical Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Koon Ho Rha,

Affiliation Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Jae Myun Lee ,

* E-mail: sjhong346@yuhs.ac (SJH); jaemyun@yuhs.ac (JML)

Affiliations Department of Microbiology, Yonsei University College of Medicine, Seoul, Republic of Korea, Brain Korea 21 Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯
Sung Joon Hong

* E-mail: sjhong346@yuhs.ac (SJH); jaemyun@yuhs.ac (JML)

Affiliation Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
⨯

Reduction of the CD16⁻CD56^bright NK Cell Subset Precedes NK Cell Dysfunction in Prostate Cancer

Kyo Chul Koo,
Doo Hee Shim,
Chang Mo Yang,
Saet-Byul Lee,
Shi Mun Kim,
Tae Young Shin,
Kwang Hyun Kim,
Ho Geun Yoon,
Koon Ho Rha,
Jae Myun Lee

Published: November 4, 2013
https://doi.org/10.1371/journal.pone.0078049

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NK cells
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Prostate cancer
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Head and neck cancers
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Metastasis
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Cancers and neoplasms
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