Inhibition of sPLA2-IIA Prevents LPS-Induced Neuroinflammation by Suppressing ERK1/2-cPLA2α Pathway in Mice Cerebral Cortex

Open Access

Peer-reviewed

Research Article

Inhibition of sPLA₂-IIA Prevents LPS-Induced Neuroinflammation by Suppressing ERK1/2-cPLA₂α Pathway in Mice Cerebral Cortex

Yanxiao Xiang,

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯
Lin Chen,

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯
Huiqing Liu,

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯
Xiaoqian Liu,

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯
Xinbing Wei,

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯
Baozhu Sun,

Affiliation Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, PR China
⨯
Tian Wang,

Affiliation Department of Pharmacology, Yantai University School of Pharmacy, Yantai, Shandong, PR China
⨯
Xiumei Zhang

* E-mail: zhangxm@sdu.edu.cn

Affiliation Department of Pharmacology, Shandong University School of Medicine, Jinan, Shandong, PR China
⨯

Astrocytes
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Phosphorylation
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Central nervous system
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Inflammation
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Cerebral cortex
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Inflammatory diseases
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Microglial cells
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Prostaglandins
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